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I've found the only was to know with semi auto 22s is to test them with various types. The bulk box ammo has proven to be the most problematic. If important that the gun goes bang (almost) every time, my experience says the 100 round packs of CCI have the fewest misfires. My 2 Ruger 10/22s generally run fine on standard (subsonic) velocity CCI. An Appleseed instructor once told me that it is slightly more accurate than the "high velocity" stuff due to the fact that the boolits never have to fall back through the turbulence of the sound barrier.