
[JMO]
According to the terminal ballistics experts the ,same ones that help design self defense ammo, and several federal studies, the only thing that reliabley stops an attacker is bullet penetration and bullet expansion. The bullet must penetrate deep enough to reach vital organs (at less than optimal angles) and it must make a large hole in order to promote rapid bleeding. Barring a central nervous hit bleeding it the only other reliable stopping mechanism in a pistol round. There is no "shock" or "knock down" factor the bullet will not tear or crush any more tissue via shock or velocity it only wound by what tissue comes into contact with the bullet itself. Having said that a bullet that expands, and penetrates a minimum of 12" in calibrated ballistics gel which studies have shown very closely relate to the penetration and expansion to real life officer involved shootings, is all that is need. There are several +p and non +p rounds that meet this performance so I've never seen the need for +p+ ammo and I prefer the heavier bullet at standard pressure because gives less muzzle blast.
[/JMO]